Tuesday, 6 June 2017

Miliary TBC



TBC lung (Miliary Tuberculosis) Human c.s.
Motic's BA410E Plan APO 4X | Moticam 10

Tuberculosis is an infectious disease. It is caused by the filamentary tubercle bacillus Mycobacterium tuberculosis an actinomycete. It was discovered in 1882 by Robert Koch, it attacks the various organs of the body. Miliary tuberculosis occurs when the bacilli are spread from a primary infection by the blood and produce a big number of small tubercles (nodules) in other parts of the body, mainly in the lungs.


Clinically, acute miliary tuberculosis, often is a typhoid-like illness that begins shortly after the initial infection, especially in children and adolescents. The tissue
responds to the attack of the bacilli by the formation of nodules, hence the name tuberculosis.



TBC lung (Miliary Tuberculosis) Human c.s.
Motic's BA410E Plan APO 10X | Moticam 10

The schematic section through a nodule shows the mass of the tubercle bacilli and destroyed cells, surrounded by a zone of nuclear fragments and enclosed by epithelioid cells. The latter develop from macrophages and are characterized by their broad, ovoid nucleus with loosely distributed chromatin and are arranged like an epithelium, hence their name. Numerous nuclei of bean-shaped giant cells lie eccentric. Groups of lymphocytes are distributed more in the periphery of the tubercle.


An advanced stage of tuberculosis is characterized by bacilli being released from the tubercles, often after years, infecting and destroying other organs (kidneys, adrenal glands, bones, joints, spleen, etc.)


TBC lung (Miliary Tuberculosis) Human c.s.
Motic's BA410E Plan APO 40X | Moticam 10



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